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The EMBO Journal<p><a href="https://sciencemastodon.com/tags/MARCH5" class="mention hashtag" rel="tag">#<span>MARCH5</span></a>-dependent <a href="https://sciencemastodon.com/tags/NLRP3" class="mention hashtag" rel="tag">#<span>NLRP3</span></a> <a href="https://sciencemastodon.com/tags/ubiquitination" class="mention hashtag" rel="tag">#<span>ubiquitination</span></a> is required for <a href="https://sciencemastodon.com/tags/mitochondrial" class="mention hashtag" rel="tag">#<span>mitochondrial</span></a> NLRP3-NEK7 complex formation and NLRP3 <a href="https://sciencemastodon.com/tags/inflammasome" class="mention hashtag" rel="tag">#<span>inflammasome</span></a> activation<br /><a href="https://www.embopress.org/doi/full/10.15252/embj.2023113481" target="_blank" rel="nofollow noopener noreferrer" translate="no"><span class="invisible">https://www.</span><span class="ellipsis">embopress.org/doi/full/10.1525</span><span class="invisible">2/embj.2023113481</span></a></p>
The EMBO Journal<p>Which <a href="https://sciencemastodon.com/tags/immune" class="mention hashtag" rel="tag">#<span>immune</span></a> pathways (beyond <a href="https://sciencemastodon.com/tags/TLRs" class="mention hashtag" rel="tag">#<span>TLRs</span></a>) control <a href="https://sciencemastodon.com/tags/otitis" class="mention hashtag" rel="tag">#<span>otitis</span></a> media and <a href="https://sciencemastodon.com/tags/COPD" class="mention hashtag" rel="tag">#<span>COPD</span></a>-inducing <a href="https://sciencemastodon.com/tags/Moraxella" class="mention hashtag" rel="tag">#<span>Moraxella</span></a> catarrhalis <a href="https://sciencemastodon.com/tags/infection" class="mention hashtag" rel="tag">#<span>infection</span></a>?</p><p>Si-Ming Man and colleagues from Australian National University reveal requirement for <a href="https://sciencemastodon.com/tags/guanylate" class="mention hashtag" rel="tag">#<span>guanylate</span></a>-binding GBP proteins and <a href="https://sciencemastodon.com/tags/caspase11" class="mention hashtag" rel="tag">#<span>caspase11</span></a>-<a href="https://sciencemastodon.com/tags/NLRP3" class="mention hashtag" rel="tag">#<span>NLRP3</span></a> <a href="https://sciencemastodon.com/tags/inflammasomes" class="mention hashtag" rel="tag">#<span>inflammasomes</span></a></p><p><a href="https://www.embopress.org/doi/10.15252/embj.2022112558" target="_blank" rel="nofollow noopener noreferrer" translate="no"><span class="invisible">https://www.</span><span class="ellipsis">embopress.org/doi/10.15252/emb</span><span class="invisible">j.2022112558</span></a></p>
Thiago Carvalho<p>'Gefitinib (GF), the tyrosine kinase inhibitor (TKI) targeting epidermal growth factor receptor, initiates lung <a href="https://qoto.org/tags/inflammation" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>inflammation</span></a> through the NLR family pyrin domain containing 3 (NLRP3) inflammasome. However, the molecular targets and mechanisms underlying the inflammatory action of GF remain unknown. In this study, we identified mitochondrial Src family kinases (mSFKs) as key determinants of GF-induced <a href="https://qoto.org/tags/NLRP3" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>NLRP3</span></a> <a href="https://qoto.org/tags/inflammasome" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>inflammasome</span></a> activation.'</p><p><a href="https://journals.aai.org/jimmunol/article-abstract/doi/10.4049/jimmunol.2200611/238968/The-NLRP3-Inflammasome-Works-as-a-Sensor-for?redirectedFrom=fulltext" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://</span><span class="ellipsis">journals.aai.org/jimmunol/arti</span><span class="invisible">cle-abstract/doi/10.4049/jimmunol.2200611/238968/The-NLRP3-Inflammasome-Works-as-a-Sensor-for?redirectedFrom=fulltext</span></a></p>